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In-stock Machinery

ELKON PAULETTE - Winnipeg Free Press Passages

PAULETTE ELKON July 9, 1915 - October 8, 2019 . Sadly, on Tuesday, October 8, we had to say good-bye to our wonderful mom, grandma, aunt, and friend, Paulette. She was born on July 9, 1915 in Winnipeg's North End, the eldest of the three children of Gregory and Anna Matkosky. She attended Margaret Scott and Isaac Newton schools.

Faculty Healthcare Innovation

Dr. Ran Elkon PhD in Bioinformatics, Tel Aviv University. Dr. Elkon is the principal investigator at the bioinformatics research lab for gene regulation at the Sackler School of Medicine, Tel Aviv University.

GitHub - ElkonLab/scAPA: This is a package and a shell script

scAPA. This is a package and a shell script for alternative polyadenylation (APA) analysis of 3' tag single-cell RNA-seq data. The shell script "scAPAscript.R" takes as input BAM files generated by 10x 3' tag RNA seq pipline and the results of cell clustering.

Study finds widespread misinterpretation of gene expression data

Dec 18, 2019 · The study was conducted by Dr. Shir Mandelbaum, Dr. Zohar Manber, Dr. Orna Elroy-Stein and Dr. Ran Elkon at TAU's Sackler Faculty of Medicine and George S. Wise Faculty of Life Sciences and was ...

BMC Genomics BioMed Central

BioMed Central Page 1 of 16 (page number not for citation purposes) BMC Genomics Research article Open Access Functional genomic delineation of TLR-induced transcriptional networks Ran Elkon†1, Chaim Linhart†2, Yonit Halperin2, Yosef Shiloh1 and Ron Shamir*2

Tel Aviv University study finds widespread misinterpretation

The study was conducted by Dr. Shir Mandelbaum, Dr. Zohar Manber, Dr. Orna Elroy-Stein and Dr. Ran Elkon at TAU's Sackler Faculty of Medicine and George S. Wise Faculty of Life Sciences and was ...

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Staff Directory

Tel Aviv University, P.O. Box 39040, Tel Aviv 6997801, Israel. UI/UX Basch_Interactive Basch_Interactive

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Volume 46 Issue 2 | Nucleic Acids Research

Cover: Fluctuation localization imaging-based fluorescence in situ hybridization (fliFISH) relies on on-off duty cycles of photoswitchable dyes to provide quantitative thresholds between true signals, emitted from an RNA copy (blue) hybridized with multiple oligonucleotide probes (yellow), and background noise.

Ikzf2/helios is a key transcriptional regulator of outer hair

Nov 21, 2018 · Cochlear tissues were then dissociated for fluorescence activated cell sorting (FACS) following the method described in Elkon et al., 2015 8. Briefly, the sensory epithelia from Anc80-eGFP and Anc80-Ikzf2 injected mice were pooled separately into 2 wells of a 48-well plate containing 0.5 mg/ml Thermolysin (Sigma). Tissues were incubated at 37 ...

Recurrent functional misinterpretation of RNA-seq data caused

Analysis of numerous RNA-seq datasets reveals a recurrent sample-specific length bias that causes frequent false positive calls by gene-set enrichment analyses, leading to functional misinterpretation of the data. Its removal requires methods that allow the integration of gene length as sample-specific covariate.

In silico identification of transcriptional regulators associated with

The development of powerful experimental strategies for functional genomics and accompanying computational tools has brought major advances in the delineation of transcriptional networks in organisms ranging from yeast to human.

ATM-dependent and -independent dynamics of the nuclear

The double-strand break (DSB) is a cytotoxic DNA lesion caused by oxygen radicals, ionizing radiation, and radiomimetic chemicals. Cells cope with DNA damage by activating the DNA damage response (DDR), which leads either to damage repair and cellular survival or to programmed cell death.

2018 Archive - UMSOM Expert Discovers Key Gene in Cells

Hertzano’s group, in collaboration with Ran Elkon, PhD, Senior Lecturer, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine in Tel Aviv, Israel took a bioinformatics and functional genomics approach to discover a gene critical for the regulation of genes involved in outer hair cell development. Bowl’s group ...

Functional genetic screens for enhancer elements in the human

Jan 11, 2016 · CRISPR-Cas9 is used for both enrichment and dropout screens of functional enhancers in human cells. Systematic identification of noncoding regulatory elements has, to date, mainly relied on large ...

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Yosef Shiloh | PhD | Tel Aviv University, Tel Aviv

Ran Elkon Yosef Shiloh The DNA damage response (DDR) is a vast signaling network that is robustly activated by DNA double-strand breaks, the critical lesion induced by ionizing radiation (IR).

November 2019: Elkon: Technical bias in RNA sequencing

A new study by Dr. Ran Elkon, Edmond J. Safra faculty fellow (Medicine) and colleagues, identifies a frequent technical bias in RNA-seq data.. Reproducibility is a major challenge in experimental biology, and with the increasing complexity of data generated by genomic-scale techniques this concern is immensely amplified.

Elkon, Ran - Netherlands Cancer Institute

Ran Elkon Experience My bioinformatics research is focused on different post-transcriptional layers of gene regulation, including microRNAs, RNA-binding proteins, alternative polyadenylation (APA) and protein translation, and understanding how mis-regulation of these layers is associated with human disease, especially cancer.

Characterization of noncoding regulatory DNA in the human

Genome-wide mapping of regulatory elements will improve our understanding of how genetic variation in the noncoding genome affects disease phenotypes. Genetic variants associated with common ...

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Beatrice Milon's research works

Beatrice Milon's 20 research works with 105 citations and 844 reads, including: Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty

Previous years – Ron Shamir's lab

Ran Elkon, Chaim Linhart, Roded Sharan, Ron Shamir, and Yosef Shiloh Genome Research Vol. 13(5), pp. 773-780, (2003) (website and supplementary material) Identifying Blocks and Sub-Populations in Noisy SNP Data

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More Info Dr. Ran Elkon Arison School of Business; Lauder School of Government, Diplomacy & Strategy 03-6409038 [email protected]: More Info Ms. Liat Erel Arison School of Business [email protected]: Mr. Naveh Eskinazi Arison School of Business [email protected]: More Info Dr. Dafna Eylon Arison School of Business [email protected]

BRD7 is a candidate tumour suppressor gene required for p53

Oncogene-induced senescence is a p53-dependent defence mechanism against uncontrolled proliferation. Consequently, many human tumours harbour p53 mutations and others show a dysfunctional p53 pathway, frequently by unknown mechanisms.

CT-FOCS: a novel method for inferring cell type-specific

Jul 18, 2019 · Spatiotemporal gene expression patterns are governed to a large extent by enhancer elements, typically located distally from their target genes. Identification of enhancer-promoter (EP) links that are specific and functional in individual cell types is a key challenge in understanding gene regulation. We introduce CT-FOCS, a new statistical inference method that utilizes multiple replicates ...

2020 SBM Remax 200 Track Mount Impact Recycler – 000970

SAVE 40% ON FUEL with the diesel-electric drive 2020 SBM Remax 200 Portable Track Mount Impact Crusher. Weighing only 27,500 KG., all drive components are electrically driven from the Tier 5 Cummins on-plant diesel-genset. This closed circuit plant uses a large 1.2 m x 2.5 m single deck screen to recirculate over size material back […]

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